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Dr. Candance Pert and her team find neurotransmitter and neuropeptide receptors on the cell walls of both the immune system and the brain.

J. E. Blalock discovers a bidirectional circuit linking the immune system with the endocrine system.

Pert CB, Ruff MR, Weber RJ, Herkenham M. Neuropeptides and their receptors: a psychosomatic network. J Immunol 1985 Aug;135(2 Suppl):820s-826s.

J.E. Blalock, E.M. Smith. A complete regulatory loop between the immune and neuroendocrine systems. Fed. Proc., 44 (1985), pp. 108-111.