Skip to main content

KPNI / Clinical PNI: The next step in clinical practice

Clinical Psychoneuroimmunology (KPNI / Clinical PNI / cPNI) is an advanced and complete medicine that provides an integrative overview of patients’ health.

It examines interconnected body systems and their relationship with psychological, social and ecological aspects of the patient’s life.

As the founders of KPNI, the Pruimboom Institute’s mission is to integrate this translational medical discipline into healthcare. Our final goal, to overcome disease and regain health.

Are you a medical or paramedical professional?
What can KPNI bring to your patient care?
  • 01.
    It helps you to focus on people, not just symptoms.
  • 02.
    It transforms your practice from reactive to proactive by addressing the origin of disease.
  • 03.
    It provides you with an in depth health model based on the interconnection between neurological, endocrinological, immune and metabolic systems from an evolutionary perspective.
  • 04.
    It empowers your patients to take a leading role in their health and wellbeing.
Disciplines: General medicine / Endocrinology and nutrition / Obstetrics and gynaecology / Sports medicine / Traumatology / Dermatology / Odontology / Psychiatry / Pediatrics / Oncology / Virology / Physiotherapy / Osteopathy / Nursing / Psychology / Internal medicine / Cardiology / Neurology / Immunology / Sociology
Take your healthcare practice to the next level
Explore all our academic offerings


Our courses are developed by recognized clinical psychoneuroimmunology researchers, all of whom also work as clinicians/therapists.


Become an accredited Clinical Psychoneuroimmunology therapist by completing our three-year master’s program.


Contribute to the growing body of knowledge in KPNI. More information on our PhD programs coming soon.

Dr. Leo Pruimboom sitting looking to the right
Dr. Leo Pruimboom, PhD

KPNI Founder
Director of the Pruimboom Institute.

A life dedicated to science and the study of KPNI in medicine

Dr. Leo Pruimboom is a physiologist and medical biochemist who has dedicated over 3 decades to studying and developing KPNI, combining research with clinical practice and teaching. He is also responsible for the development of the Intermittent Living concept, based on biomarker analysis, that uses ancient stressful stimuli to improve health.

How can we help you?
Whether you’re interested in signing up for a course, or want to know more about KPNI, we would love to hear from you. Please allow up to 48 hours for us to get back to you.